Endocrine Abstracts

Introduction: Considering the high prevalence and significant morbidity and mortality of heart failure in type 2 diabetic patients, identification of risk factors for cardiac dysfunction is important. The ejection fraction represents how well the heart is pumping out blood and is used to diagnose heart failure. In this study, we investigated the factors associated with left ventricular ejection fraction (LVEF) in type 2 diabetic patients.Methods: A total...

Renal tubulointerstitial fibrosis is a common feature of the final stage of nearly all cause types of chronic kidney disease. Although classic peroxisome proliferator-activated receptor-gamma (PPARγ) agonists have a protective effect on diabetic nephropathy, much less is known about their direct effects in renal fibrosis. This study aimed to investigate possible beneficial effects of lobeglitazone, a novel PPARγ agonist, on renal fibrosis in mice with unilateral uret...

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Aims: High level of uric acid is known to associate with stroke, coronary artery disease and metabolic syndrome. Some epidemiologic studies suggested that high uric acid level is connected with dyslipidemia. However, this relationship was not examined in type 2 diabetic patients. This study was conducted to investigate the association between serum uric acid level and lipid profiles in type 2 diabetic patients.Methods: A total of 972 type 2 diabetes pati...

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